Iminodiacetic Acid
Iminodiacetic Acid
Iminodiacetic Acid
Iminodiacetic Acid
Iminodiacetic Acid
Iminodiacetic Acid

Iminodiacetic Acid (IDA) CAS 142-73-4 98% High-purity Raw Material for Glyphosate Synthesis

CAS Number 142-73-4
Chemical Name Iminodiacetic acid
Molecular Weight 133.10 g/mol
Molecular Formula C₄H₇NO₄
Synonyms N-(Carboxymethyl)glycine; IDA; 2,2′-Iminodiacetic acid; Glycine, N-(carboxymethyl)-
EINECS 205-555-4
Appearance White crystalline powder or granules
Solubility Soluble in water; slightly soluble in ethanol; insoluble in ether, acetone, and benzene
Storage conditions Store in a dry, well-ventilated area; keep tightly sealed to prevent moisture absorption; avoid contact with strong oxidizers and acids
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Parameters:

CAS Number 142-73-4
Chemical Name Iminodiacetic acid
Molecular Weight 133.10 g/mol
Molecular Formula C₄H₇NO₄
Synonyms N-(Carboxymethyl)glycine; IDA; 2,2'-Iminodiacetic acid; Glycine, N-(carboxymethyl)-
EINECS 205-555-4
Appearance White crystalline powder or granules
Solubility Soluble in water; slightly soluble in ethanol; insoluble in ether, acetone, and benzene
Storage conditions Store in a dry, well-ventilated area; keep tightly sealed to prevent moisture absorption; avoid contact with strong oxidizers and acids
Melting point Decomposes above 243°C
Boiling point Not applicable (decomposes before reaching boiling point)
Density Approximately 1.56 g/cm³ at 20°C
Vapor pressure Negligible at room temperature (≤0.01 mmHg at 25°C)
Refractive index Not applicable (solid state)
Flash point Not applicable (non-flammable solid)
Water solubility ~2.4 g/100 mL at 25°C
BRN 1743768
LogP Approximately -2.7 (estimated, due to high polarity from carboxyl groups)

 

Application：

 

Core raw material for glyphosate synthesis, supporting herbicide production：


One of the mainstream processes for the industrial production of glyphosate is the "IDA method," and IDA is the starting material for this process:
Step 1: IDA reacts with formaldehyde and phosphorous acid under acidic conditions to generate PMIDA (N-(phosphonomethyl)iminodiacetic acid), the direct precursor of glyphosate.
Step 2: PMIDA is converted to glyphosate via oxidation reactions (e.g., oxidation with hydrogen peroxide).

By providing the structural units of imino (-NH-) and carboxyl (-COOH) groups in its molecule, IDA offers the framework for the key active group of glyphosate (phosphonomethylamino group), serving as the basis for the formation of the glyphosate molecular structure.

 

Indirectly ensuring the application effect of herbicides：


As a non-selective broad-spectrum herbicide, glyphosate is widely used in:
Weed control in fields of genetically modified glyphosate-resistant crops (such as soybeans, corn, and cotton);
Weed eradication in scenarios like non-cultivated land (e.g., along railways and highways), orchards, and tea gardens (by inhibiting the EPSPS enzyme in plants, blocking amino acid synthesis, and causing weeds to wither).

 

Safety and Storage：

 

Hazards: Low toxicity (LD₅₀ rat oral > 3000 mg/kg). However, dust may irritate the respiratory tract; a dust mask should be worn during operation. Avoid mixing with strong oxidizers (such as potassium permanganate) to prevent decomposition.

 

Storage: Store in sealed containers in a dry, well-ventilated warehouse. Keep away from fire sources and acidic substances. Shelf life is 12 months.

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