3-Methylpyridine
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Name：
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3-Methylpyridine；β-Picoline
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CAS No：
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108-99-6
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Molecular Formula：
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C₆H₇N
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Molecular Weight：
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93.13 g/mol
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EINECS No：
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203-636-9
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MDL No：
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MFCD00006353
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Parameters
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Parameter Item
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Details
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Name
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3-Methylpyridine；β-Picoline
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CAS No.
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108-99-6
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Molecular Formula
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C₆H₇N
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Molecular Weight
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93.13 g/mol
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EINECS No.
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203-636-9
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MDL No.
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MFCD00006353
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Appearance
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Colorless to pale yellow liquid with a strong pungent odor.
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Melting Point
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-19.5℃
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Boiling Point
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143-144℃ (at atmospheric pressure)
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Density
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0.957 g/cm³ (20℃)
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Refractive Index
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1.504 (n₂₀/D)
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Flash Point
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36℃ (closed cup), classified as a flammable liquid.
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Solubility
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Slightly soluble in water (approximately 40 g/L, 20℃); easily soluble in organic solvents such as ethanol, diethyl ether, benzene, and acetone.
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Vapor Pressure
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1.33 kPa (39℃)
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Stability
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Stable but volatile; reacts violently with strong oxidants and acids.
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Main Uses
Chemical Intermediate: Used in the synthesis of pharmaceutical products such as nicotinic acid (vitamin B3), nicotinamide, and isoniazid (anti-tuberculosis drug).
Pesticide Raw Material: Serves as an intermediate in the preparation of insecticides, fungicides (e.g., pyridine fungicides), and herbicides.
Dyes and Fragrances: Used as a raw material in the synthesis of azo dyes, rubber additives, and certain fragrances.
Solvent: Acts as a polar aprotic solvent, used to dissolve various compounds in organic synthesis reactions.
Analytical Reagent: Used as an indicator or extractant in chemical analysis.
Safety and Storage
Hazards:
Flammable; its vapors can form explosive mixtures with air, and may ignite or explode when exposed to open flames or high heat.
Strongly irritating to skin, eyes, and mucous membranes; inhalation can cause respiratory tract damage, and ingestion can lead to gastrointestinal burns.
Toxic to aquatic organisms; avoid contamination of water bodies.
Storage Conditions:
Seal and store in a cool, well-ventilated warehouse, away from fire sources and heat sources, with temperature not exceeding 30℃.
Store separately from oxidants, acids, and food chemicals; do not mix storage.
Equip with appropriate types and quantities of fire-fighting equipment, and the storage area should have leakage emergency treatment equipment.
Emergency Treatment:
Skin contact: Immediately remove contaminated clothing, rinse thoroughly with plenty of flowing water for at least 15 minutes, and seek medical attention.
Eye contact: Lift the eyelids, rinse with physiological saline for 15 minutes, and seek medical attention.
Inhalation: Quickly move to a place with fresh air, keep the respiratory tract unobstructed, and seek medical attention with oxygen if necessary.
Leakage treatment: Absorb the leaked material with sand or vermiculite, avoid entering sewers, and strictly keep away from open flames.
Environmental Impact
Classified as a hazardous chemical; emissions must comply with environmental protection standards to avoid entry into soil, water bodies, or the atmosphere.
Waste must be disposed of as hazardous waste and must not be dumped arbitrarily.
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